Advances in Diagnosis and Management of Cutaneous Adverse Drug Reactions by Neil H. Shear & Roni P. Dodiuk-Gad

Author:Neil H. Shear & Roni P. Dodiuk-Gad
Language: eng
Format: epub
ISBN: 9789811314896
Publisher: Springer Singapore

Chemotherapy-induced alopecia (CIA)

Incidence: 65% (Trueb 2010)

Chemotherapy-induced acute reversible alopecia

Taxanes are one of the top CIA-inducing drugs (Trueb 2010; Tallon et al. 2010)

Chemotherapy-induced acute reversible alopecia is commonly induced by anagen effluvium and typically occurs after the first treatment cycle (Trueb 2007). Any hair-bearing areas (scalp hair, eyelashes, eyebrows, beard, axillae, pubis, and body) can be involved. The hair usually starts to regrow 3–6 months after the last cycle of chemotherapy and gradually returns to baseline with one third of patients undergoing texture and color change of the regrown hair (Lindner et al. 2012)

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